Biplab Bose
Associate Professor, Department of Biosciences and Bioengineering
IIT Guwahati
Biplab Bose received his Ph. D in Biochemistry from All India Institute of Medical Sciences, New Delhi, India. Prior to that he had received M. Pharm and B. Pharm degree from Jadavpur University, Kolkata, India. He joined IIT Guwahati in 2006. He has developed an online course on Dynamical Models in Biology (available through NPTEL and YouTube).
Biplab is interested in understanding design principles in living systems. Notably, he is interested to know the effect of architecture, kinetics and integration of molecular pathways on information transmission, and emergent phenomena. He is also exploring stochasticity in cell biology, particularly cellular heterogeneity in gene expression and molecular processes. His lab at IIT Guwahati uses experimental as well as mathematical tools to explore the questions. His group has also developed a freeware – FlowPy for for flowcytometry data analysis.
Principal Investigator
Further information
Research interest in relevance of the project
Biplab Bose is interested in understanding design principles in living systems. Notably, he is interested to know the effect of architecture, kinetics and integration of molecular pathways on information transmission, and emergent phenomena. He is also exploring stochasticity in cell biology, particularly cellular heterogeneity in gene expression and molecular processes. His lab at IIT Guwahati uses experimental as well as mathematical tools to explore the questions. His group has also developed a freeware – FlowPy for for flowcytometry data analysis.
Field of Expertise
- Cell biology
- Mathematical Biology
Selected publications
- Dutta P., Devaraj V., Bose B. A Negative Feedback Regulates The Flow Of Signal Through Akt/mTORC1/S6K1 Pathway. bioRxiv147710; doi:https://doi.org/10.1101/147710
- Loying P, Manhas J, Sen S, Bose B. Autoregulation and Heterogeneity in Expression of Human Cripto-1. PLoS ONE. 201510(2): e0116748
- Bose B. Systems biology: A biologist’s viewpoint. Prog Biophys Mol Biol. 2013 113(3): 358-68
- Bose B, Sinha S. Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen driven affinity selection. Immunology. 2005 116(2):172-83.
Contact details
Address:
Department of Biosciences and Bioengineering
Indian Institute of Technology Guwahati
PIN – 781039
Phone: +91 361 258 2216
Fax: +91 361 2582249
