Dieter W. Heermann
Vice-Rector International Affairs of Heidelberg University
Dieter W. Heermann group pursues research at the forefront of physics and quantitative biology with emphasis on mathematical modelling and analysis of biological data, development of computational methods, systems biology, biophysics, biomathematics, artificial intelligence and general data science methods in these fields. With his team he develops and applies predictive models for biological and biophysical systems and their interactions at multiple scales, and create statistical methods for the analysis of the complex correlated data. His research team is actively engaged in joint projects with experimental biologists and physicists producing such big data resources.
Principal Investigator | Supervisor
Projects/students/activities within this project
- Artificial intelligence method for the analysis of chromosomal conformation capture data
- Structural changes of chromosomes induced by radiation
- Persistent Homology algorithm for high resolution microscopy images
- DNA/Protein binding modelling
Research interest of relevance
- Chromosomes structure
- Relation between the gene network and the physical structure of chromosomes
- Physical models for gene regulation
- Modelling of cell regulatory networks
- Modelling of the synaptonemal complex
- Genomics and proteomics
- Modelling of tumor growth
- Data science methods
- Image analysis
- Protein binding
Field of Expertise
- Heermann, D.W. Computer Simulation Methods of Theoretical Physics, Springer Verlag, Heidelberg, (1986).
- Binder, K. and Heermann, D.W. Monte Carlo Simulation in Statistical Mechanics: An Introduction. Springer Verlag, Heidelberg, (1988).
- Di Ventura, B., Knecht, B., Andreas, H., Godinez, W. J., Fritsche, M., Rohr, K., Nickel, W., Heermann, D. W., Sourjik, V.
- William J. Chromosome segregation by the Escherichia coli Min system. Molecular Systems Biology 9 Article number: 686. (2013). doi:10.1038/msb.2013.44
- Lei, L. and Heermann, D.W. The interaction of DNA with multi-Cys2His2 zinc finger proteins. Journal of Physics: Condensed Matter 27(6):064107 (2015). doi: 10.1088/0953-8984/27/6/064107.
- Bohn, M. and Heermann, D. W. Repulsive Forces Between Looping Chromosomes Induce Entropy-Driven Segregation. PLoS ONE 6(1): e14428. (2011). doi:10.1371/journal.pone. 0014428
Network within RTG Bio Big Data Research